1gq8
From Proteopedia
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| - | [[Image:1gq8.gif|left|200px]]<br /><applet load="1gq8" size=" | + | [[Image:1gq8.gif|left|200px]]<br /><applet load="1gq8" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1gq8, resolution 1.75Å" /> | caption="1gq8, resolution 1.75Å" /> | ||
'''PECTIN METHYLESTERASE FROM CARROT'''<br /> | '''PECTIN METHYLESTERASE FROM CARROT'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1GQ8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Daucus_carota Daucus carota] with CAC as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Pectinesterase Pectinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.11 3.1.1.11] Known structural/functional Site: <scene name='pdbsite=AC2:Cac A 502 Binding Site'>AC2</scene>. Full crystallographic information is available from [http:// | + | 1GQ8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Daucus_carota Daucus carota] with <scene name='pdbligand=CAC:'>CAC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Pectinesterase Pectinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.11 3.1.1.11] Known structural/functional Site: <scene name='pdbsite=AC2:Cac+A+502+Binding+Site'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQ8 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: pectin methylesterase]] | [[Category: pectin methylesterase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:41:50 2008'' |
Revision as of 07:41, 3 February 2008
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PECTIN METHYLESTERASE FROM CARROT
Overview
Pectin is a principal component in the primary cell wall of plants. During, cell development, pectin is modified by pectin methylesterases to give, different properties to the cell wall. This report describes the first, crystal structure of a plant pectin methylesterase. The beta-helical, structure embodies a central cleft, lined by several aromatic residues, that has been deduced to be suitable for pectin binding. The active site, is found at the center of this cleft where Asp157 is suggested to act as, the nucleophile, Asp136 as an acid/base and Gln113/Gln135 to form an anion, hole to stabilize the transition state.
About this Structure
1GQ8 is a Single protein structure of sequence from Daucus carota with as ligand. Active as Pectinesterase, with EC number 3.1.1.11 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Crystal structure of plant pectin methylesterase., Johansson K, El-Ahmad M, Friemann R, Jornvall H, Markovic O, Eklund H, FEBS Lett. 2002 Mar 13;514(2-3):243-9. PMID:11943159
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