3s3m
From Proteopedia
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Revision as of 05:48, 5 October 2011
Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and Dolutegravir (S/GSK1349572)
Template:ABSTRACT PUBMED 21719464
About this Structure
3s3m is a 4 chain structure with sequence from Human spumaretrovirus. Full crystallographic information is available from OCA.
Reference
- Hare S, Smith SJ, Metifiot M, Jaxa-Chamiec A, Pommier Y, Hughes SH, Cherepanov P. Structural and Functional Analyses of the Second-generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572). Mol Pharmacol. 2011 Jun 30. PMID:21719464 doi:10.1124/mol.111.073189
Categories: Human spumaretrovirus | Cherepanov, P. | Hare, S. | Dna integration | Dna-binding | Endonuclease | Hhcc motif | Inhibitor | Metal-binding | Multifunctional enzyme | Nuclease | Nucleotidyltransferase | Nucleus | Protein-dna complex | Recombination | Recombination-inhibitor-dna complex | Tetramer | Transferase | Viral nucleoprotein | Viral protein | Virion | Zinc binding