3pnh

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'''Unreleased structure'''
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[[Image:3pnh.jpg|left|200px]]
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The entry 3pnh is ON HOLD until Paper Publication
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{{STRUCTURE_3pnh| PDB=3pnh | SCENE= }}
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Authors: Delker, S.L., Li, H., Poulos, T.L.
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===Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in complex with 6-(((3R,4R)-4-(2-((2-FLUORO-2-(3-FLUOROPHENYL) ETHYL)AMINO)ETHOXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE===
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Description: Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in complex with 6-(((3R,4R)-4-(2-((2-FLUORO-2-(3-FLUOROPHENYL) ETHYL)AMINO)ETHOXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:32:29 2010''
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{{ABSTRACT_PUBMED_21809851}}
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==About this Structure==
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[[3pnh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNH OCA].
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==Reference==
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<ref group="xtra">PMID:021809851</ref><references group="xtra"/>
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[[Category: Bos taurus]]
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[[Category: Nitric-oxide synthase]]
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[[Category: Delker, S L.]]
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[[Category: Li, H.]]
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[[Category: Poulos, T L.]]
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[[Category: Heme enzyme]]
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[[Category: Inhibitor]]
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[[Category: Oxidoreductase-inhibitor complex]]

Revision as of 06:39, 5 October 2011

Image:3pnh.jpg

Template:STRUCTURE 3pnh

Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in complex with 6-(((3R,4R)-4-(2-((2-FLUORO-2-(3-FLUOROPHENYL) ETHYL)AMINO)ETHOXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE

Template:ABSTRACT PUBMED 21809851

About this Structure

3pnh is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Kraus JM, Labby KJ, Ji H, Mataka J, Xia G, Li H, Delker SL, Roman LJ, Martasek P, Poulos TL, Silverman RB. Improved Synthesis of Chiral Pyrrolidine Inhibitors and Their Binding Properties to Neuronal Nitric Oxide Synthase. J Med Chem. 2011 Sep 22;54(18):6399-6403. Epub 2011 Aug 22. PMID:21809851 doi:10.1021/jm200411j

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