3s7a

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'''Unreleased structure'''
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[[Image:3s7a.jpg|left|200px]]
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The entry 3s7a is ON HOLD until Paper Publication
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{{STRUCTURE_3s7a| PDB=3s7a | SCENE= }}
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Authors: Cody, V., Pace, J., Nowak, J.
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===Human dihydrofolate reductase binary complex with PT684===
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Description: Human dihydrofolate reductase binary complex with PT684
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{{ABSTRACT_PUBMED_21931219}}
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==About this Structure==
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[[3s7a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S7A OCA].
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==Reference==
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<ref group="xtra">PMID:021931219</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Homo sapiens]]
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[[Category: Cody, V.]]
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[[Category: Nowak, J.]]
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[[Category: Pace, J.]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Reductase]]
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[[Category: Single polypeptide chain]]

Revision as of 06:40, 5 October 2011

Template:STRUCTURE 3s7a

Human dihydrofolate reductase binary complex with PT684

Template:ABSTRACT PUBMED 21931219

About this Structure

3s7a is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cody V, Pace J, Nowak J. Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpter idine reveals an unusual binding mode. Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):875-80. Epub 2011, Sep 8. PMID:21931219 doi:10.1107/S0907444911030071

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