3s7a
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3s7a.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3s7a", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3s7a| PDB=3s7a | SCENE= }} | ||
- | + | ===Human dihydrofolate reductase binary complex with PT684=== | |
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21931219}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21931219 is the PubMed ID number. | ||
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+ | {{ABSTRACT_PUBMED_21931219}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3s7a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S7A OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021931219</ref><references group="xtra"/> | ||
+ | [[Category: Dihydrofolate reductase]] | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Cody, V.]] | ||
+ | [[Category: Nowak, J.]] | ||
+ | [[Category: Pace, J.]] | ||
+ | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
+ | [[Category: Reductase]] | ||
+ | [[Category: Single polypeptide chain]] |
Revision as of 06:40, 5 October 2011
Human dihydrofolate reductase binary complex with PT684
Template:ABSTRACT PUBMED 21931219
About this Structure
3s7a is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cody V, Pace J, Nowak J. Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpter idine reveals an unusual binding mode. Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):875-80. Epub 2011, Sep 8. PMID:21931219 doi:10.1107/S0907444911030071