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Fructose-1,6-bisphosphatase

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(New page: Crystal Structure of Fructose-1,6-bisphosphatase 1bk4 {{STRUCTURE_1bk4| PDB=1bk4 | SIZE=300| SCENE= |right|CAPTION=Fructose-1,6-bisphosphatase [[1...)
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{{STRUCTURE_1bk4| PDB=1bk4 | SIZE=300| SCENE= |right|CAPTION=Fructose-1,6-bisphosphatase [[1bk4]] }}
{{STRUCTURE_1bk4| PDB=1bk4 | SIZE=300| SCENE= |right|CAPTION=Fructose-1,6-bisphosphatase [[1bk4]] }}
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Fructose-1,6-bisphosphatase (FBP) is an enzyme in the glucose generating pathway which converts fructose-1,6-bisphosphate to fructose 6-phosphate (F6P).
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Fructose-1,6-bisphosphatase (FBP) is an enzyme in the glucose generating pathway which converts fructose-1,6-bisphosphate to fructose 6-phosphate (F6P). The images at the left and at the right correspond to one representative FBP, ''i.e.'' the crystal structure of Fructose-1,6-bisphosphatase from rabbit ([[1bk4]]).
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1bk4 – FBP – rabbit
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{{TOC limit|limit=2}}
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1d9q – peFBP – pea
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<br />
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1dbz, 1dcu – peFBP (mutant)
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<br />
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1fj6, 1fj9, 1yxi, 2f3b, 2f3d, 2f3h - pFBP (mutant) – pig
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<br />
-
3bih - EcFBP GlpX (mutant) - Escherichia coli
+
<br />
 +
<br />
-
FBP binary complexes
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== 3D Structures of Fructose-1,6-bisphosphatase ==
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1fta – hFBP + AMP – human
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[[1bk4]] – FBP – rabbit<br />
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2fhy, 2fie, 2fix, 2jjk, 2vt5, 3a29, 2wbb, 2wbd, 3kbz, 3kc0, 3kc1, 2y5k, 2y5l - hFBP + inhibitor
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[[1d9q]] – peFBP – pea<br />
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3ifa - hFBP (mutant) + AMP
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[[1dbz]], [[1dcu]] – peFBP (mutant)<br />
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1fpk – pFBP + Tl
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[[1fj6]], [[1fj9]], [[1yxi]], [[2f3b]], [[2f3d]], [[2f3h]] - pFBP (mutant) – pig<br />
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1yyz, 1yz0 - pFBP (mutant) + AMP
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[[3bih]] - EcFBP GlpX (mutant) - ''Escherichia coli''<br />
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1kz8, 1lev, 1q9d – pFBP + inhibitor
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2qvu, 2qvv - pFBP + F6-di-P
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2gq1 – EcFBP + sulfate
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2r8t - EcFBP GlpX + F6P
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3big - EcFBP GlpX (mutant) + phosphate
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3d1r - EcFBP GlpX (mutant) + F6P
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-
FBP ternary complexes
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===FBP binary complexes===
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3ifc - hFBP (mutant) + AMP + F6P
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[[1fta]] – hFBP + AMP – human<br />
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1fpi, 1fpj, 1fpl – pFBP + AMP + glucitol bisphosphate
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[[2fhy]], [[2fie]], [[2fix]], [[2jjk]], [[2vt5]], [[3a29]], [[2wbb]], [[2wbd]], [[3kbz]], [[3kc0]], [[3kc1]], [[2y5k]], [[2y5l]] - hFBP + inhibitor<br />
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1cnq – pFBP + Zn + F6P
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[[3ifa]] - hFBP (mutant) + AMP<br />
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1eyi, 1nuw, 1nux, 1nuy, 1nuz, 1nv0, 1nv1, 1nv2, 1nv3 - pFBP + phosphate + F6P
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[[1fpk]] – pFBP + Tl<br />
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1nv4, 1nv5, 1nv6 - pFBP + phosphate + EDTA + F6P
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[[1yyz]], [[1yz0]] - pFBP (mutant) + AMP<br />
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1eyj, 1eyk, 1nv7 - pFBP + phosphate + AMP + F6P
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[[1kz8]], [[1lev]], [[1q9d]] – pFBP + inhibitor<br />
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2owz – EcFBP + citrate + F6P
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[[2qvu]], [[2qvv]] - pFBP + F6-di-P<br />
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2qvr - EcFBP + citrate + F6-di-P
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[[2gq1]] – EcFBP + sulfate <br />
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2ox3 - EcFBP + PEP + F6P
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[[2r8t]] - EcFBP GlpX + F6P<br />
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[[3big]] - EcFBP GlpX (mutant) + phosphate<br />
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[[3d1r]] - EcFBP GlpX (mutant) + F6P<br />
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 +
===FBP ternary complexes===
 +
 
 +
[[3ifc]] - hFBP (mutant) + AMP + F6P<br />
 +
[[1fpi]], [[1fpj]], [[1fpl]] – pFBP + AMP + glucitol bisphosphate<br />
 +
[[1cnq]] – pFBP + Zn + F6P<br />
 +
[[1eyi]], [[1nuw]], [[1nux]], [[1nuy]], [[1nuz]], [[1nv0]], [[1nv1]], [[1nv2]], [[1nv3]] - pFBP + phosphate + F6P<br />
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[[1nv4]], [[1nv5]], [[1nv6]] - pFBP + phosphate + EDTA + F6P<br />
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[[1eyj]], [[1eyk]], [[1nv7]] - pFBP + phosphate + AMP + F6P<br />
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[[2owz]] – EcFBP + citrate + F6P<br />
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[[2qvr]] - EcFBP + citrate + F6-di-P<br />
 +
[[2ox3]] - EcFBP + PEP + F6P<br />
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[[Category:Topic Page]]

Revision as of 07:00, 28 October 2011

Image:1bk4.png
Crystal Structure of Fructose-1,6-bisphosphatase 1bk4

Template:STRUCTURE 1bk4

Fructose-1,6-bisphosphatase (FBP) is an enzyme in the glucose generating pathway which converts fructose-1,6-bisphosphate to fructose 6-phosphate (F6P). The images at the left and at the right correspond to one representative FBP, i.e. the crystal structure of Fructose-1,6-bisphosphatase from rabbit (1bk4).

Contents






3D Structures of Fructose-1,6-bisphosphatase

1bk4 – FBP – rabbit
1d9q – peFBP – pea
1dbz, 1dcu – peFBP (mutant)
1fj6, 1fj9, 1yxi, 2f3b, 2f3d, 2f3h - pFBP (mutant) – pig
3bih - EcFBP GlpX (mutant) - Escherichia coli

FBP binary complexes

1fta – hFBP + AMP – human
2fhy, 2fie, 2fix, 2jjk, 2vt5, 3a29, 2wbb, 2wbd, 3kbz, 3kc0, 3kc1, 2y5k, 2y5l - hFBP + inhibitor
3ifa - hFBP (mutant) + AMP
1fpk – pFBP + Tl
1yyz, 1yz0 - pFBP (mutant) + AMP
1kz8, 1lev, 1q9d – pFBP + inhibitor
2qvu, 2qvv - pFBP + F6-di-P
2gq1 – EcFBP + sulfate
2r8t - EcFBP GlpX + F6P
3big - EcFBP GlpX (mutant) + phosphate
3d1r - EcFBP GlpX (mutant) + F6P

FBP ternary complexes

3ifc - hFBP (mutant) + AMP + F6P
1fpi, 1fpj, 1fpl – pFBP + AMP + glucitol bisphosphate
1cnq – pFBP + Zn + F6P
1eyi, 1nuw, 1nux, 1nuy, 1nuz, 1nv0, 1nv1, 1nv2, 1nv3 - pFBP + phosphate + F6P
1nv4, 1nv5, 1nv6 - pFBP + phosphate + EDTA + F6P
1eyj, 1eyk, 1nv7 - pFBP + phosphate + AMP + F6P
2owz – EcFBP + citrate + F6P
2qvr - EcFBP + citrate + F6-di-P
2ox3 - EcFBP + PEP + F6P

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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