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3t9t
From Proteopedia
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| - | + | [[Image:3t9t.png|left|200px]] | |
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| + | {{STRUCTURE_3t9t| PDB=3t9t | SCENE= }} | ||
| - | + | ===Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21958547}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21958547 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21958547}} | ||
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| + | ==About this Structure== | ||
| + | [[3t9t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9T OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021958547</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Caspers, N.]] | ||
| + | [[Category: Han, S.]] | ||
| + | [[Category: Alpha/beta]] | ||
| + | [[Category: Atp binding]] | ||
| + | [[Category: Intracellular]] | ||
| + | [[Category: Kinase domain]] | ||
| + | [[Category: Phosphorylation]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 07:07, 30 October 2011
Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline
Template:ABSTRACT PUBMED 21958547
About this Structure
3t9t is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kim KH, Maderna A, Schnute ME, Hegen M, Mohan S, Miyashiro J, Lin L, Li E, Keegan S, Lussier J, Wrocklage C, Nickerson-Nutter CL, Wittwer AJ, Soutter H, Caspers N, Han S, Kurumbail R, Dunussi-Joannopoulos K, Douhan J 3rd, Wissner A. Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6258-63. Epub 2011 Sep 10. PMID:21958547 doi:10.1016/j.bmcl.2011.09.008
