2xa4

(Difference between revisions)

Revision as of 07:16, 30 October 2011

2xa4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Ioannidis S, Lamb ML, Wang T, Almeida L, Block MH, Davies AM, Peng B, Su M, Zhang HJ, Hoffmann E, Rivard C, Green I, Howard T, Pollard H, Read J, Alimzhanov M, Bebernitz G, Bell K, Ye M, Huszar D, Zinda M. Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol -3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway. J Med Chem. 2011 Jan 13;54(1):262-76. Epub 2010 Dec 7. PMID:21138246 doi:10.1021/jm1011319

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-{{Seed}}
+[[Image:2xa4.png|left|200px]]
-[[Image:2xa4.jpg|left|200px]]
 <!--
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 ===INHIBITORS OF JAK2 KINASE DOMAIN===
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_21138246}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 21138246 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_21138246}}
 ==About this Structure==
-XA4 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XA4 OCA].
+[[2xa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XA4 OCA].
+==Reference==
+<ref group="xtra">PMID:021138246</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Green, I.]]
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 [[Category: Proto-oncogene]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:38:54 2010''