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1qj4
From Proteopedia
(New page: 200px<br /> <applet load="1qj4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qj4, resolution 1.10Å" /> '''HYDROXYNITRILE-LYAS...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1QJ4 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.39 4.2.1.39]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJ4 OCA]]. | + | 1QJ4 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Gluconate_dehydratase Gluconate dehydratase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.39 4.2.1.39]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJ4 OCA]]. |
==Reference== | ==Reference== | ||
Atomic resolution crystal structure of hydroxynitrile lyase from Hevea brasiliensis., Gruber K, Gugganig M, Wagner UG, Kratky C, Biol Chem. 1999 Jul-Aug;380(7-8):993-1000. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10494852 10494852] | Atomic resolution crystal structure of hydroxynitrile lyase from Hevea brasiliensis., Gruber K, Gugganig M, Wagner UG, Kratky C, Biol Chem. 1999 Jul-Aug;380(7-8):993-1000. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10494852 10494852] | ||
| + | [[Category: Gluconate dehydratase]] | ||
[[Category: Hevea brasiliensis]] | [[Category: Hevea brasiliensis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: oxynitrilase]] | [[Category: oxynitrilase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:32:26 2007'' |
Revision as of 10:27, 30 October 2007
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HYDROXYNITRILE-LYASE FROM HEVEA BRASILIENSIS AT ATOMIC RESOLUTION
Overview
The X-ray crystal structure of native hydroxynitrile lyase from Hevea, brasiliensis (Hb-HNL) has been determined at 1.1 A resolution. It refined, to a final R of 11.5% for all data and an Rfree of 14.4%. The favorable, data-to-parameter ratio at atomic resolution made the refinement of, individual anisotropic displacement parameters possible. The data also, allowed a clear distinction of the alternate orientations of all histidine, and the majority of asparagine and glutamine side chains. A number of, hydrogen atoms, including one on the imidazole of the mechanistically, important His-235, became visible as peaks in a difference electron, density map. The structure revealed a discretely disordered sidechain of, Ser-80, which is part of the putative catalytic triad. Analysis of the, ... [(full description)]
About this Structure
1QJ4 is a [Single protein] structure of sequence from [Hevea brasiliensis] with SO4 and GOL as [ligands]. Active as [Gluconate dehydratase], with EC number [4.2.1.39]. Structure known Active Site: CAT. Full crystallographic information is available from [OCA].
Reference
Atomic resolution crystal structure of hydroxynitrile lyase from Hevea brasiliensis., Gruber K, Gugganig M, Wagner UG, Kratky C, Biol Chem. 1999 Jul-Aug;380(7-8):993-1000. PMID:10494852
Page seeded by OCA on Tue Oct 30 12:32:26 2007
