3sx4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
[[Image:3sx4.png|left|200px]]
-
The entry 3sx4 is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3sx4", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3sx4| PDB=3sx4 | SCENE= }}
-
Authors: Klei, H.E.
+
===Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one===
-
Description: Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)-2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one
+
 
 +
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_21996520}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 21996520 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_21996520}}
 +
 
 +
==About this Structure==
 +
[[3sx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX4 OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:021996520</ref><references group="xtra"/>
 +
[[Category: Dipeptidyl-peptidase IV]]
 +
[[Category: Homo sapiens]]
 +
[[Category: Klei, H E.]]
 +
[[Category: Alpha/beta hydrolase fold]]
 +
[[Category: Aminopeptidase]]
 +
[[Category: Beta barrel]]
 +
[[Category: Beta propeller]]
 +
[[Category: Dimer]]
 +
[[Category: Dpp4]]
 +
[[Category: Exopeptidase]]
 +
[[Category: Glycoprotein]]
 +
[[Category: Hydrolase-hydrolase inhibitor complex]]
 +
[[Category: Membrane]]
 +
[[Category: Protease]]
 +
[[Category: Protein:inhibitor complex]]
 +
[[Category: Secreted]]
 +
[[Category: Serine protease]]
 +
[[Category: Signal- anchor]]
 +
[[Category: Transmembrane]]

Revision as of 09:17, 30 October 2011

Image:3sx4.png

Template:STRUCTURE 3sx4

Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one

Template:ABSTRACT PUBMED 21996520

About this Structure

3sx4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang W, Devasthale P, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Li YX, Zahler R, Kirby MS, Hamann LG. 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6646-51. Epub 2011 Sep 24. PMID:21996520 doi:10.1016/j.bmcl.2011.09.074

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3sx4"
Personal tools