1mem
From Proteopedia
(Difference between revisions)
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| - | [[Image:1mem.gif|left|200px]]<br /><applet load="1mem" size=" | + | [[Image:1mem.gif|left|200px]]<br /><applet load="1mem" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1mem, resolution 1.8Å" /> | caption="1mem, resolution 1.8Å" /> | ||
'''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR'''<br /> | '''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1MEM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with BZP and BNS as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] Known structural/functional Site: <scene name='pdbsite=CAT:Description Not Provided'>CAT</scene>. Full crystallographic information is available from [http:// | + | 1MEM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BZP:'>BZP</scene> and <scene name='pdbligand=BNS:'>BNS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] Known structural/functional Site: <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MEM OCA]. |
==Reference== | ==Reference== | ||
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[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:53:31 2008'' |
Revision as of 07:53, 3 February 2008
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CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR
Disease
Known disease associated with this structure: Pycnodysostosis OMIM:[601105]
About this Structure
1MEM is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Cathepsin K, with EC number 3.4.22.38 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587
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