3tza

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m (Protected "3tza" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3tza.png|left|200px]]
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The entry 3tza is ON HOLD
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{{STRUCTURE_3tza| PDB=3tza | SCENE= }}
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Authors: Frydenvang, K., Kastrup, J.S.
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===Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution===
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Description: Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution
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{{ABSTRACT_PUBMED_21923187}}
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==About this Structure==
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[[3tza]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus,_synthetic,_rattus_norvegicus Rattus norvegicus, synthetic, rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZA OCA].
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==Reference==
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<ref group="xtra">PMID:021923187</ref><references group="xtra"/>
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[[Category: Rattus norvegicus, synthetic, rattus norvegicus]]
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[[Category: Frydenvang, K.]]
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[[Category: Kastrup, J S.]]
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[[Category: Ampa receptor ligand-binding domain]]
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[[Category: Antagonist]]
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[[Category: Glua2-s1s2j]]
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[[Category: Membrane protein]]

Revision as of 09:27, 30 October 2011

Image:3tza.png

Template:STRUCTURE 3tza

Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution

Template:ABSTRACT PUBMED 21923187

About this Structure

3tza is a 2 chain structure with sequence from Rattus norvegicus, synthetic, rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Szymanska E, Frydenvang K, Contreras-Sanz A, Pickering DS, Frola E, Serafimoska Z, Nielsen B, Kastrup JS, Johansen TN. A New Phenylalanine Derivative Acts as an Antagonist at the AMPA Receptor GluA2 and Introduces Partial Domain Closure: Synthesis, Resolution, Pharmacology, and Crystal Structure. J Med Chem. 2011 Oct 27;54(20):7289-98. Epub 2011 Oct 4. PMID:21923187 doi:10.1021/jm200862h

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OCA

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