2ykc
From Proteopedia
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- | + | [[Image:2ykc.png|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_2ykc", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
+ | or leave the SCENE parameter empty for the default display. | ||
+ | --> | ||
+ | {{STRUCTURE_2ykc| PDB=2ykc | SCENE= }} | ||
- | + | ===TRICYCLIC SERIES OF HSP90 INHIBITORS=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21972823}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21972823 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21972823}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[2ykc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YKC OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021972823</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Dupuy, A.]] | ||
+ | [[Category: Vallee, F.]] | ||
+ | [[Category: Chaperone]] | ||
+ | [[Category: Inhibition]] |
Revision as of 10:11, 30 October 2011
TRICYCLIC SERIES OF HSP90 INHIBITORS
Template:ABSTRACT PUBMED 21972823
About this Structure
2ykc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Vallee F, Carrez C, Pilorge F, Dupuy A, Parent A, Bertin L, Thompson F, Ferrari P, Fassy F, Lamberton A, Thomas A, Arrebola R, Guerif S, Rohaut A, Certal V, Ruxer JM, Delorme C, Jouanen A, Dumas J, Grepin C, Combeau C, Goulaouic H, Dereu N, Mikol V, Mailliet P, Minoux H. Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2011 Oct 27;54(20):7206-19. Epub 2011 Oct 5. PMID:21972823 doi:10.1021/jm200784m