1oek
From Proteopedia
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| - | [[Image:1oek.jpg|left|200px]]<br /><applet load="1oek" size=" | + | [[Image:1oek.jpg|left|200px]]<br /><applet load="1oek" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1oek, resolution 2.4Å" /> | caption="1oek, resolution 2.4Å" /> | ||
'''YODA FROM ESCHERICHIA COLI CRYSTALLISED WITH ZINC IONS'''<br /> | '''YODA FROM ESCHERICHIA COLI CRYSTALLISED WITH ZINC IONS'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1OEK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Zn Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http:// | + | 1OEK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OEK OCA]. |
==Reference== | ==Reference== | ||
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[[Category: yoda]] | [[Category: yoda]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:57:04 2008'' |
Revision as of 07:57, 3 February 2008
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YODA FROM ESCHERICHIA COLI CRYSTALLISED WITH ZINC IONS
Overview
We have determined the crystal structure of YodA, an Escherichia coli, protein of unknown function. YodA had been identified under conditions of, cadmium stress, and we confirm that it binds metals such as cadmium and, zinc. We have also found nickel bound in one of the crystal forms. YodA is, composed of two domains: a main lipocalin/calycin-like domain and a, helical domain. The principal metal-binding site lies on one side of the, calycin domain, thus making YodA the first metal-binding lipocalin known., Our experiments suggest that YodA expression may be part of a more general, stress response. From sequence analogy with the C-terminal domain of a, metal-binding receptor of a member of bacterial ATP-binding cassette, transporters, we propose a three-dimensional model for this receptor and, suggest that YodA may have a receptor-type partner in E. coli.
About this Structure
1OEK is a Single protein structure of sequence from Escherichia coli with as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
YodA from Escherichia coli is a metal-binding, lipocalin-like protein., David G, Blondeau K, Schiltz M, Penel S, Lewit-Bentley A, J Biol Chem. 2003 Oct 31;278(44):43728-35. Epub 2003 Aug 8. PMID:12909634
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Categories: Escherichia coli | Single protein | Blondeau, K. | David, G. | Lewit-Bentley, A. | Penel, S. | Renouard, M. | ZN | Lipocalin | Stress protein | Yoda
