3vhe
From Proteopedia
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- | + | [[Image:3vhe.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3vhe", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3vhe| PDB=3vhe | SCENE= }} | ||
- | + | ===Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_20833055}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 20833055 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_20833055}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3vhe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VHE OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:020833055</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Receptor protein-tyrosine kinase]] | ||
+ | [[Category: Awazu, Y.]] | ||
+ | [[Category: Hori, A.]] | ||
+ | [[Category: Imanura, S.]] | ||
+ | [[Category: Iwata, H.]] | ||
+ | [[Category: Kamiyama, K.]] | ||
+ | [[Category: Miki, H.]] | ||
+ | [[Category: Miyamoto, N.]] | ||
+ | [[Category: Oguro, Y.]] | ||
+ | [[Category: Okada, K.]] | ||
+ | [[Category: Takagi, T.]] | ||
+ | [[Category: Kinase]] | ||
+ | [[Category: Kinase domain]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 08:22, 2 November 2011
Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.
Template:ABSTRACT PUBMED 20833055
About this Structure
3vhe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. Epub 2010 Aug 13. PMID:20833055 doi:10.1016/j.bmc.2010.08.017