This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1n90
From Proteopedia
(New page: 200px<br /> <applet load="1n90" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n90, resolution 2.90Å" /> '''FOLLOWING THE C HEM...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1N90 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]] with HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.2 1.9.3.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N90 OCA]]. | + | 1N90 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]] with HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Transferred_entry:_1.7.2.1 Transferred entry: 1.7.2.1]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.2 1.9.3.2]]. Structure known Active Sites: NIA and NIB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N90 OCA]]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Transferred entry: 1.7.2.1]] | ||
[[Category: Cambillau, C.]] | [[Category: Cambillau, C.]] | ||
[[Category: Nurizzo, D.]] | [[Category: Nurizzo, D.]] | ||
| Line 27: | Line 28: | ||
[[Category: pseudomonas aeruginosa]] | [[Category: pseudomonas aeruginosa]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:36:10 2007'' |
Revision as of 10:31, 30 October 2007
|
FOLLOWING THE C HEME REDUCTION IN NITRITE REDUCTASE FROM PSEUDOMONAS AERUGINOSA
Overview
The structures of nitrite reductase from Paracoccus denitrificans GB17, (NiR-Pd) and Pseudomonas aeruginosa (NiR-Pa) have been described for the, oxidized and reduced state (Fulop, V., Moir, J. W. B., Ferguson, S. J., and Hajdu, J. (1995) Cell 81, 369-377; Nurizzo, D., Silvestrini, M. C., Mathieu, M., Cutruzzola, F., Bourgeois, D., Fulop, V., Hajdu, J., Brunori, M., Tegoni, M., and Cambillau, C. (1997) Structure 5, 1157-1171; Nurizzo, D., Cutruzzola, F., Arese, M., Bourgeois, D., Brunori, M., Cambillau, C. , and Tegoni, M. (1998) Biochemistry 37, 13987-13996). Major conformational, rearrangements are observed in the extreme states although they are more, substantial in NiR-Pd. The four structures differ significantly in the c, heme domains. Upon reduction, a His17/Met106 heme-ligand ... [(full description)]
About this Structure
1N90 is a [Single protein] structure of sequence from [Pseudomonas aeruginosa] with HEC and DHE as [ligands]. Active as [Transferred entry: 1.7.2.1], with EC number [1.9.3.2]. Structure known Active Sites: NIA and NIB. Full crystallographic information is available from [OCA].
Reference
Does the reduction of c heme trigger the conformational change of crystalline nitrite reductase?, Nurizzo D, Cutruzzola F, Arese M, Bourgeois D, Brunori M, Cambillau C, Tegoni M, J Biol Chem. 1999 May 21;274(21):14997-5004. PMID:10329702
Page seeded by OCA on Tue Oct 30 12:36:10 2007
