1qks
From Proteopedia
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| - | [[Image:1qks.jpg|left|200px]]<br /><applet load="1qks" size=" | + | [[Image:1qks.jpg|left|200px]]<br /><applet load="1qks" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1qks, resolution 1.28Å" /> | caption="1qks, resolution 1.28Å" /> | ||
'''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''<br /> | '''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1QKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans] with SO4, HEC, DHE and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=C1A:The C Haem Is The Point Of Electron Entry'>C1A</scene>, <scene name='pdbsite=C1B:The C Haem Is The Point Of Electron Entry'>C1B</scene>, <scene name='pdbsite=D1A:The D1 Haem Is The Site Of Catalytic Acti'>D1A</scene> and <scene name='pdbsite=D1B:The D1 Haem Is The Site Of Catalytic Acti'>D1B</scene>. Full crystallographic information is available from [http:// | + | 1QKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=HEC:'>HEC</scene>, <scene name='pdbligand=DHE:'>DHE</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=C1A:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1A</scene>, <scene name='pdbsite=C1B:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1B</scene>, <scene name='pdbsite=D1A:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1A</scene> and <scene name='pdbsite=D1B:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1B</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA]. |
==Reference== | ==Reference== | ||
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[[Category: periplasmic]] | [[Category: periplasmic]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:00:46 2008'' |
Revision as of 08:00, 3 February 2008
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CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM
Overview
Cytochrome cd1-nitrite reductase is a bifunctional enzyme that catalyzes, the one-electron reduction of nitrite to nitric oxide and the, four-electron reduction of oxygen to water. The 1.55 A crystal structure, of the dimeric enzyme from Thiosphaera pantotropha is reported here. The, protein was sequenced from the X-ray structure. Each subunit contains a, covalent c heme with two axial His ligands (His-17, His-69) and a unique, noncovalent d1 heme ligated by Tyr-25 and His-200. The d1 heme is the, mononuclear iron center where both oxygen and nitrite reduction take, place. The two types of heme are located in separate domains whose, arrangement suggests a mechanism requiring domain movement during, catalysis.
About this Structure
1QKS is a Single protein structure of sequence from Paracoccus denitrificans with , , and as ligands. Known structural/functional Sites: , , and . Full crystallographic information is available from OCA.
Reference
The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1., Fulop V, Moir JW, Ferguson SJ, Hajdu J, Cell. 1995 May 5;81(3):369-77. PMID:7736589
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Categories: Paracoccus denitrificans | Single protein | Fulop, V. | DHE | GOL | HEC | SO4 | Denitrification | Electron transport | Enzyme | Nitrite reductase | Oxidoreductase | Periplasmic
