Alkaline phosphatase
From Proteopedia
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| + | {{STRUCTURE_1q1p| PDB=1q1p | SIZE=300| SCENE=Cadherin/Cv/1 |right|CAPTION=Cadherin, [[1q1p]] }} | ||
'''Alkaline phosphatase''' (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment. | '''Alkaline phosphatase''' (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment. | ||
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| + | == 3D Structures of alkaline phosphatase == | ||
[[1alk]], [[1ed9]], [[1ed8]] – EcALP + Zn + Mg – ''Eschechia coli''<br /> | [[1alk]], [[1ed9]], [[1ed8]] – EcALP + Zn + Mg – ''Eschechia coli''<br /> | ||
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[[3mk0]], [[3mk1]] - hALP + Zn + Mg + phosphate + nitrophenol + phosphoserine<br /> | [[3mk0]], [[3mk1]] - hALP + Zn + Mg + phosphate + nitrophenol + phosphoserine<br /> | ||
[[3mk2]] - hALP + Zn + Mg + phosphoserine<br /> | [[3mk2]] - hALP + Zn + Mg + phosphoserine<br /> | ||
| - | [[2iuc]] - AbALP + Zn + Mg + phosphate – Antarctic bacterium | + | [[2iuc]] - AbALP + Zn + Mg + phosphate – Antarctic bacterium<br /> |
[[2w5v]], [[2w5x]] - AbALP (mutant) + Zn + Mg + phosphoserine<br /> | [[2w5v]], [[2w5x]] - AbALP (mutant) + Zn + Mg + phosphoserine<br /> | ||
[[2w5w]] - AbALP (mutant) + Zn + phosphoserine<br /> | [[2w5w]] - AbALP (mutant) + Zn + phosphoserine<br /> | ||
[[2x98]] - ALP + Zn + Mg + phosphate – ''Halobacterium salinarum'' | [[2x98]] - ALP + Zn + Mg + phosphate – ''Halobacterium salinarum'' | ||
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| + | [[Category:Topic Page]] | ||
Revision as of 10:02, 3 November 2011
Alkaline phosphatase (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment.
{TOC limit|limit=2}}
3D Structures of alkaline phosphatase
1alk, 1ed9, 1ed8 – EcALP + Zn + Mg – Eschechia coli
3bdh - EcALP + Mg
1aja, 3bdf, 3bdg – EcALP (mutant)
1ali, 1ajb, 1ajc, 1ajd, 1alj, 1ani, 1anj, 2anh, 1hqa, 1urb, 1hjk, 1khk, 1kh7 - EcALP (mutant) + Zn + Mg
1ura - EcALP (mutant) + Zn
1khn - EcALP (mutant) + Zn
1b8j - EcALP + Zn + Mg + VO4
1kh5 - EcALP (mutant) + Zn + Mg + AlF3
1khj - EcALP (mutant) + Zn + AlF3
1k7h – nsALP + Zn + maleic acid – northern shrimp
1shq - nsALP + Zn + Mg
1zeb - hALP + Zn + Mg – human
1zef - hALP + Zn + Mg + phenylalanine
2glq - hALP + Zn + Mg + Sr
3e2d – ALP + Zn + Mg – Vibrio
3a52 - ALP + Zn + Mg – Shewanella
ALP complexes with phosphate derivative
1khl, 3dyc - EcALP (mutant) + Zn + phosphate
1alh - EcALP + Zn + phosphate
1y6v - EcALP + Co + phosphate
1y7a - EcALP (mutant) + Co + phosphate
1elx, 1ely, 1elz, 1kh9, 1kh4, 2g9y, 3cmr - EcALP (mutant) + Zn + Mg + phosphate
3dpc - EcALP (mutant) + phosphorylated peptide
2ga3 - EcALP (mutant) + Zn + Mg + phosphothreonine
1ew8 - EcALP + Zn + phosphonoacetic acid + phosphate
1ew9 - EcALP + Zn + Mg + mercaptomethyl phosphonate
1shn - nsALP + Zn + phosphate
1zed - hALP + Zn + Mg + PO3 + nitrophenyl hydrogen methylphosphonate
3mk0, 3mk1 - hALP + Zn + Mg + phosphate + nitrophenol + phosphoserine
3mk2 - hALP + Zn + Mg + phosphoserine
2iuc - AbALP + Zn + Mg + phosphate – Antarctic bacterium
2w5v, 2w5x - AbALP (mutant) + Zn + Mg + phosphoserine
2w5w - AbALP (mutant) + Zn + phosphoserine
2x98 - ALP + Zn + Mg + phosphate – Halobacterium salinarum
