Annexin
From Proteopedia
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[[Image:1ain.png|left|200px|thumb|Crystal Structure of Human Annexin I, [[1ain]]]] | [[Image:1ain.png|left|200px|thumb|Crystal Structure of Human Annexin I, [[1ain]]]] | ||
| - | {{STRUCTURE_1ain| PDB=1ain | SIZE=300| SCENE=Annexin/Cv/2 |right|CAPTION=Human Annexin I, [[1ain]] }} | + | {{STRUCTURE_1ain| PDB=1ain | SIZE=300| SCENE=Annexin/Cv/2 |right|CAPTION=Human Annexin I complex with Ca+2 ions, [[1ain]] }} |
[[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. In the annexin image calcium ions are shown as green balls. | [[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. In the annexin image calcium ions are shown as green balls. | ||
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| + | ==3D structures of annexin== | ||
| + | ''Update November 2011'' | ||
== Annexin I == | == Annexin I == | ||
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[[1anw]], [[1avh]], [[1avr]] - hAnV<br /> | [[1anw]], [[1avh]], [[1avr]] - hAnV<br /> | ||
[[1anx]] - hAnV+Ca<br /> | [[1anx]] - hAnV+Ca<br /> | ||
| + | [[2xo2]] – hAnV + Ca + azidohomoalanine<br /> | ||
| + | [[2xo3]] - hAnV + Ca + homopropargylglycine | ||
Revision as of 10:44, 7 November 2011
Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. In the annexin image calcium ions are shown as green balls.
Contents |
3D structures of annexin
Update November 2011
Annexin I
2q4c, 1ycn - AnI - Arabidopsis thaliana
1mcx, 1hm6 - pAnI - pig
1qls - pAnI head+calgizzarrin
1bo9 - hAnI head - human NMR
1ain - hAnI
Annexin II
2hyu, 2hyv - hAnII+heparin oligosaccharide
2hyw, 1xjl - hAnII+Ca
1w7b - hAnII
1bt6 - hAnII head+calpactin light chain
Annexin III
Annexin IV
2zhi, 2zhj, rAnIV+Na - rat
2zoc - hAnIV
1i4a - cAnIV (mutant) - cow
1aow, 1ann - cAnIV
Annexin V
2ie6, 2ie7, rAnV
1n41, 1n42, 1n44, 2h0k, 2h0l, 2h0m, 1bc0, 1bc1, 1bc3, 1bcw, 1bcy, 1bcz - rAnV (mutant)
1g5n - rAnV+ heparin oligosaccharide
1a8a, 1a8b - rAnV+phospholipid analog
2ran - rAnV+Ca
1yii – chAnV+Ca – chicken
1yj0 - chAnV+Zn
1ala - ChAnV
1hak - hAnV+K-201
1sav - hAnV (thioproline)
1hvd, 1hve, 1hvf, 1hvg - hAnV (mutant)
1anw, 1avh, 1avr - hAnV
1anx - hAnV+Ca
2xo2 – hAnV + Ca + azidohomoalanine
2xo3 - hAnV + Ca + homopropargylglycine
Annexin VI
1m9i - hAnVI (mutant)
1avc - cAnVI+Ca
Annexin VIII
1w3w - hAnVIII
1w45 - hAnVIII (mutant)
Annexin XII
1dm5 - HvAnXII (mutant) - Hydra vulgaris
1aei - HvAnXII
Other annexins
1dk5 - An24 - Capsicom annuum
3brx - coAnGH1+Ca - cotton
1n00 - coAnGH1
