1urr
From Proteopedia
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| - | [[Image:1urr.gif|left|200px]]<br /><applet load="1urr" size=" | + | [[Image:1urr.gif|left|200px]]<br /><applet load="1urr" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1urr, resolution 1.50Å" /> | caption="1urr, resolution 1.50Å" /> | ||
'''A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)'''<br /> | '''A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1URR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with GOL as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Acylphosphatase Acylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.7 3.6.1.7] Known structural/functional Site: <scene name='pdbsite=AC1:Gol Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http:// | + | 1URR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Acylphosphatase Acylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.7 3.6.1.7] Known structural/functional Site: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URR OCA]. |
==Reference== | ==Reference== | ||
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[[Category: enzyme]] | [[Category: enzyme]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:04:11 2008'' |
Revision as of 08:04, 3 February 2008
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A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)
Overview
Analysis of the Drosophila melanogaster EST database led to the discovery, and cloning of a novel acylphosphatase. The CG18505 gene coding for a new, enzyme (AcPDro2) is clearly distinct from the previously described, CG16870Acyp gene, which also codes for a D. melanogaster acylphosphatase, (AcPDro). The putative catalytic residues, together with residues held to, stabilize the acylphosphatase fold, are conserved in the two encoded, proteins. Crystals of AcPDro2, which belong to the trigonal space group, P3(1)21, with unit-cell parameters a = b = 45.8, c = 98.6 angstroms, gamma, = 120 degrees, allowed the solution of the protein structure by molecular, replacement and its refinement to 1.5 angstroms resolution. The AcPDro2, active-site structure is discussed.
About this Structure
1URR is a Single protein structure of sequence from Drosophila melanogaster with as ligand. Active as Acylphosphatase, with EC number 3.6.1.7 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase., Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:15159593
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