Sandbox 35
From Proteopedia
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<scene name='Sandbox_35/2nd_struc_papain_helix/2'>alpha helix</scene> <ref name="9PAP PDB">[http://www.pdb.org/pdb/explore/explore.do?structureId=9PAP]9PAP PDB</ref> | <scene name='Sandbox_35/2nd_struc_papain_helix/2'>alpha helix</scene> <ref name="9PAP PDB">[http://www.pdb.org/pdb/explore/explore.do?structureId=9PAP]9PAP PDB</ref> | ||
| - | <scene name='Sandbox_35/Active_site_papain/3'>active site</scene> <ref> | + | <scene name='Sandbox_35/Active_site_papain/3'>active site</scene> <ref group="xtra">PMID:8140097</ref> |
===Distribution of Residues=== | ===Distribution of Residues=== | ||
<scene name='Sandbox_35/Hydrophobic_papain/1'>non-polar and polar residues</scene> | <scene name='Sandbox_35/Hydrophobic_papain/1'>non-polar and polar residues</scene> | ||
Revision as of 02:51, 13 November 2011
| Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013. |
Contents |
Papain
Introduction
finds its origin from the latex of the papaya fruit and is classified as a sulfhydryl protease.
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Catalytic Mechanism
References
http://www.pdb.org/pdb/explore/explore.do?structureId=2PAD • Show the secondary structures. • Compare the distribution of polar residues to that of nonpolar residues. • Highlight the active site. • If you can find a PDB file of the enzyme that contains a pseudo-substrate (may be inhibitor), highlight it. • Show the contacts or attractions that are present between the pseudo-substrate and the protein, and if the enzyme has multiple subunits, show the contacts between the subunits. • Identify any other ligands that are present in the structure and the types of contacts that are present between them and the protein
http://proteopedia.org/wiki/index.php/Sandbox_55#cite_note-18 Table of contents Pictures References (cross links)
