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== Papain ==
== Papain ==
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<StructureSection load='9pap' size='500' side='right' caption='Structure of 9PAP with Bound Ligands (PDB entry [[9pap]])' scene='Sandbox_34/9pap_without_solvent_meoh/3'>
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<StructureSection load='9pap' size='500' side='right' caption='Structure of 9PAP (PDB entry [[9pap]])' scene='Sandbox_34/9pap_without_solvent_meoh/3'>
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<scene name='Sandbox_34/9pap_without_solvent_meoh/3'>TextToBeDisplayed</scene>
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<scene name='Sandbox_34/9pap_without_solvent_meoh/3'>9PAP Tertiary Structure</scene>
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'''Papain''' is a cysteine protease from the peptidase C1 family. It consists of only one chain, with three disulfide bonds. It contains a modified cysteine residue, <scene name='Sandbox_34/Entire_protein_with_ocs_focus/2'>cysteine sulfonic acid</scene>, with a sulfhydryl group that is necessary for the activity of the enzyme.<ref>http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/analytical-enzymes/papain.html<ref/>
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'''Papain''' is a cysteine protease from the peptidase C1 family. It consists of only one chain of 212 residues with three disulfide bonds.<ref>PMID:6502713</ref> A modified cysteine residue with a sulhydryl group is It contains a modified cysteine residue, <scene name='Sandbox_34/Entire_protein_with_ocs_focus/2'>cysteine sulfonic acid</scene>, with a sulfhydryl group that is necessary for the activity of the enzyme.<ref>http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/analytical-enzymes/papain.html</ref>
<scene name='Sandbox_34/9pap_without_ligands_bound/1'>TextToBeDisplayed</scene>
<scene name='Sandbox_34/9pap_without_ligands_bound/1'>TextToBeDisplayed</scene>

Revision as of 16:59, 13 November 2011

Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.


Papain

Structure of 9PAP (PDB entry 9pap)

Drag the structure with the mouse to rotate

References

  1. Kamphuis IG, Kalk KH, Swarte MB, Drenth J. Structure of papain refined at 1.65 A resolution. J Mol Biol. 1984 Oct 25;179(2):233-56. PMID:6502713
  2. http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/analytical-enzymes/papain.html
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