1v0m
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1v0m.jpg|left|200px]]<br /><applet load="1v0m" size=" | + | [[Image:1v0m.jpg|left|200px]]<br /><applet load="1v0m" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1v0m, resolution 1.07Å" /> | caption="1v0m, resolution 1.07Å" /> | ||
'''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5'''<br /> | '''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5'''<br /> | ||
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1V0M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans] with IMD as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] Known structural/functional Site: <scene name='pdbsite=ACB:Imd Binding Site For Chain A'>ACB</scene>. Full crystallographic information is available from [http:// | + | 1V0M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans] with <scene name='pdbligand=IMD:'>IMD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] Known structural/functional Site: <scene name='pdbsite=ACB:Imd+Binding+Site+For+Chain+A'>ACB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V0M OCA]. |
==Reference== | ==Reference== | ||
| Line 28: | Line 28: | ||
[[Category: xylanase]] | [[Category: xylanase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:13:23 2008'' |
Revision as of 08:13, 3 February 2008
|
XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5
Overview
The atomic resolution structures of xylobiose-derived isofagomine and, xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A, from Streptomyces lividans reveal undistorted (4)C(1) chair conformed, sugars and, in the case of the deoxynojirimycin analogue, suggest unusual, pK(a) changes of the enzyme's catalytic machinery upon binding.
About this Structure
1V0M is a Single protein structure of sequence from Streptomyces lividans with as ligand. Active as Endo-1,4-beta-xylanase, with EC number 3.2.1.8 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887
Page seeded by OCA on Sun Feb 3 10:13:23 2008
