1t4e
From Proteopedia
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[[Image:1t4e.png|left|200px]] | [[Image:1t4e.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015715460</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Carver, T E.]] | [[Category: Carver, T E.]] | ||
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[[Category: Schubert, C.]] | [[Category: Schubert, C.]] | ||
[[Category: Zhao, S Y.]] | [[Category: Zhao, S Y.]] | ||
| + | [[Category: Ligase]] | ||
[[Category: Mdm2-inhibitor complex]] | [[Category: Mdm2-inhibitor complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:54:35 2009'' | ||
Revision as of 10:02, 16 November 2011
Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor
Template:ABSTRACT PUBMED 15715460
About this Structure
1t4e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF. Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells. J Med Chem. 2005 Feb 24;48(4):909-12. PMID:15715460 doi:10.1021/jm049137g
