3ig6
From Proteopedia
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[[Image:3ig6.png|left|200px]] | [[Image:3ig6.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_19703768}} | {{ABSTRACT_PUBMED_19703768}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191840 191840]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3ig6]] is a 4 chain structure of [[Urokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IG6 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Urokinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019703768</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: U-plasminogen activator]] | [[Category: U-plasminogen activator]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Kringle]] | [[Category: Kringle]] | ||
| - | [[Category: Pharmaceutical]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Plasminogen activation]] | [[Category: Plasminogen activation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: S1 site inhibitor]] | [[Category: S1 site inhibitor]] | ||
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[[Category: Urokinase]] | [[Category: Urokinase]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:04:05 2010'' | ||
Revision as of 10:24, 16 November 2011
Contents |
Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Template:ABSTRACT PUBMED 19703768
About this Structure
3ig6 is a 4 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- West CW, Adler M, Arnaiz D, Chen D, Chu K, Gualtieri G, Ho E, Huwe C, Light D, Phillips G, Pulk R, Sukovich D, Whitlow M, Yuan S, Bryant J. Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5712-5. Epub 2009 Aug 7. PMID:19703768 doi:10.1016/j.bmcl.2009.08.008
Categories: Homo sapiens | U-plasminogen activator | Adler, M. | Whitlow, M. | Blood coagulation | Disulfide bond | Egf-like domain | Fibrinolysis | Glycoprotein | Hydrolase | Kringle | Phosphoprotein | Plasminogen activation | Protease | S1 site inhibitor | Secreted | Selective | Serine protease | Structure-based drug design | Urokinase | Zymogen
