1w4s
From Proteopedia
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| - | [[Image:1w4s.gif|left|200px]]<br /><applet load="1w4s" size=" | + | [[Image:1w4s.gif|left|200px]]<br /><applet load="1w4s" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1w4s, resolution 1.55Å" /> | caption="1w4s, resolution 1.55Å" /> | ||
'''CRYSTAL STRUCTURE OF THE PROXIMAL BAH DOMAIN OF POLYBROMO'''<br /> | '''CRYSTAL STRUCTURE OF THE PROXIMAL BAH DOMAIN OF POLYBROMO'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1W4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with CL as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Cl Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http:// | + | 1W4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W4S OCA]. |
==Reference== | ==Reference== | ||
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[[Category: swi/snf-b]] | [[Category: swi/snf-b]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:19:16 2008'' |
Revision as of 08:19, 3 February 2008
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CRYSTAL STRUCTURE OF THE PROXIMAL BAH DOMAIN OF POLYBROMO
Overview
The BAH domain (bromo-associated homology domain) was first identified, from a repeated motif found in the nuclear protein polybromo--a large (187, kDa) modular protein comprising six bromodomains, two BAH domains and an, HMG box. To date, the BAH domain has no ascribed function, although it is, found in a wide range of proteins that contain additional domains involved, in either transcriptional regulation (e.g. SET, PHD and bromodomain), and/or DNA binding (HMG box and AT hook). The molecular function of, polybromo itself also remains unclear, but it has been identified as a key, component of an SWI/SNF (switching/sucrose non-fermenting)-related, ATP-dependent chromatin-remodelling complex PBAF (polybromo, BRG1-associated factors; also known as SWI/SNF-B or SWI/SNFbeta). We, present in this paper the crystal structure of the proximal BAH domain, from chicken polybromo (BAH1), at a resolution of 1.6 A (1 A=0.1 nm)., Structure-based sequence analysis reveals several features that may be, involved in mediating protein-protein interactions.
About this Structure
1W4S is a Single protein structure of sequence from Gallus gallus with as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Crystal structure of the proximal BAH domain of the polybromo protein., Oliver AW, Jones SA, Roe SM, Matthews S, Goodwin GH, Pearl LH, Biochem J. 2005 Aug 1;389(Pt 3):657-64. PMID:15839835
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