2hap
From Proteopedia
(Difference between revisions)
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[[Image:2hap.png|left|200px]] | [[Image:2hap.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2hap]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAP OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009886287</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Guarente, L.]] | [[Category: Guarente, L.]] | ||
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[[Category: Zhang, L.]] | [[Category: Zhang, L.]] | ||
[[Category: Asymmetry]] | [[Category: Asymmetry]] | ||
| - | [[Category: Complex transcription factor | + | [[Category: Complex transcription factor-dna]] |
| + | [[Category: Gene regulation-dna complex]] | ||
[[Category: Hyperactive mutant]] | [[Category: Hyperactive mutant]] | ||
[[Category: Transcriptional activation]] | [[Category: Transcriptional activation]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:36:58 2009'' | ||
Revision as of 11:18, 16 November 2011
STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION
Template:ABSTRACT PUBMED 9886287
About this Structure
2hap is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- King DA, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nat Struct Biol. 1999 Jan;6(1):22-7. PMID:9886287 doi:10.1038/4893
- Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630
