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3pr0
From Proteopedia
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| - | + | [[Image:3pr0.jpg|left|200px]] | |
| - | The | + | <!-- |
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| + | {{STRUCTURE_3pr0| PDB=3pr0 | SCENE= }} | ||
| - | + | ===Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21355555}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21355555 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21355555}} | ||
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| + | ==About this Structure== | ||
| + | [[3pr0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR0 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021355555</ref><references group="xtra"/> | ||
| + | [[Category: Amidase]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Boger, D L.]] | ||
| + | [[Category: Han, G W.]] | ||
| + | [[Category: Mileni, M.]] | ||
| + | [[Category: Stevens, R C.]] | ||
| + | [[Category: Alpha-ketoheterocycle]] | ||
| + | [[Category: Endocannabinoid degradation]] | ||
| + | [[Category: Faah]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Oxadiazole]] | ||
| + | [[Category: Protein-inhibitor complex]] | ||
Revision as of 12:15, 16 November 2011
Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase
Template:ABSTRACT PUBMED 21355555
About this Structure
3pr0 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Mileni M, Garfunkle J, Ezzili C, Cravatt BF, Stevens RC, Boger DL. Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent alpha-ketoheterocycle inhibitor of fatty acid amide hydrolase. J Am Chem Soc. 2011 Mar 23;133(11):4092-100. Epub 2011 Feb 28. PMID:21355555 doi:10.1021/ja110877y
