3rwp

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'''Unreleased structure'''
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[[Image:3rwp.jpg|left|200px]]
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The entry 3rwp is ON HOLD until Paper Publication
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{{STRUCTURE_3rwp| PDB=3rwp | SCENE= }}
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Authors: Greasley, S.E., Hickey, M., Ferre, R.-A., Krauss, M., Cronin, C.
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===Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1)===
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Description: Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1)
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{{ABSTRACT_PUBMED_22040023}}
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==About this Structure==
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[[3rwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWP OCA].
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==Reference==
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<ref group="xtra">PMID:022040023</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Cronin, C.]]
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[[Category: Ferre, R A.]]
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[[Category: Greasley, S E.]]
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[[Category: Hickey, M.]]
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[[Category: Krauss, M.]]
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[[Category: Kinase domain]]
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[[Category: Phosphoserine: sep]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 12:20, 16 November 2011

Template:STRUCTURE 3rwp

Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1)

Template:ABSTRACT PUBMED 22040023

About this Structure

3rwp is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Murphy ST, Bailey S, Burke BJ, Chappie TA, Ferre R, Greasley S, Hickey MJ, Humphrey J, Kablaoui N, Kath J, Kazmirski S, Kraus M, Kupchinskey S, Li J, Marx MA, Richter D, Tanis SP, Tran K, Vernier W, Alton G, Baxi SM, Ermolieff J, Lingardo L, Xie Z, Yin MJ, Yu XH. Discovery of Novel, Potent and Selective Inhibitors of 3-Phosphoinositide-Dependent Kinase (PDK1). J Med Chem. 2011 Oct 31. PMID:22040023 doi:10.1021/jm201019k

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