3rcd

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'''Unreleased structure'''
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[[Image:3rcd.jpg|left|200px]]
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The entry 3rcd is ON HOLD until Paper Publication
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{{STRUCTURE_3rcd| PDB=3rcd | SCENE= }}
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Authors: Aertgeerts, K., Skene, R., Sogabe, S.
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===HER2 Kinase Domain Complexed with TAK-285===
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Description: HER2 Kinase Domain Complexed with TAK-285
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{{ABSTRACT_PUBMED_22003817}}
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==About this Structure==
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[[3rcd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCD OCA].
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==Reference==
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<ref group="xtra">PMID:022003817</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Aertgeerts, K.]]
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[[Category: Skene, R.]]
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[[Category: Sogabe, S.]]
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[[Category: Anti-oncogene]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Disease]]
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[[Category: Glycoprotein]]
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[[Category: Kinase domain]]
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[[Category: Membrane]]
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[[Category: Mutation]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Receptor]]
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[[Category: Secreted]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Tyrosine kinase inhibitor]]
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[[Category: Tyrosine-protein kinase]]

Revision as of 19:04, 23 November 2011

Image:3rcd.jpg

Template:STRUCTURE 3rcd

HER2 Kinase Domain Complexed with TAK-285

Template:ABSTRACT PUBMED 22003817

About this Structure

3rcd is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ishikawa T, Seto M, Banno H, Kawakita Y, Oorui M, Taniguchi T, Ohta Y, Tamura T, Nakayama A, Miki H, Kamiguchi H, Tanaka T, Habuka N, Sogabe S, Yano J, Aertgeerts K, Kamiyama K. Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold. J Med Chem. 2011 Nov 4. PMID:22003817 doi:10.1021/jm2008634

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OCA

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