DNA methyltransferase
From Proteopedia
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== 3D Structures of DNA methyltransferase == | == 3D Structures of DNA methyltransferase == | ||
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===Methylguanine DNMT=== | ===Methylguanine DNMT=== | ||
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[[3a1a]] - h-cytosine DNMT PWWP domain | [[3a1a]] - h-cytosine DNMT PWWP domain | ||
| - | [[3av4]] - m-cytosine DNMT – mouse | + | [[1g55]] - h-cytosine DNMT2 (mutant) |
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| + | [[3av4]], [[1khc]] - m-cytosine DNMT – mouse | ||
[[2c7o]], [[2c7p]], [[2c7q]], [[2c7r]], [[3pta]] – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine | [[2c7o]], [[2c7p]], [[2c7q]], [[2c7r]], [[3pta]] – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine | ||
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[[3swr]] - h-cytosine DNMT + sinefungin | [[3swr]] - h-cytosine DNMT + sinefungin | ||
| + | [[1boo]] - cytosine DNMT (mutant) – ''Proteus vulgaris'' | ||
| - | [[1fjx]] – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - Haemophilus haemolyticus | + | [[1fjx]] – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - ''Haemophilus haemolyticus'' |
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| + | [[1hmy]] – HhHaeiii DNMT + S-adenonosyl methionine | ||
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| + | [[1m0e]] - HhDNMT (mutant) + DNA + inhibitor | ||
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| + | [[2i9k]] - HhDNMT (mutant) + DNA | ||
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| + | [[2hr1]] - HhDNMT + DNA + ADOHCY | ||
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| + | [[2z6q]], [[2z6u]], [[2zcj]] - HhDNMT (mutant) + DNA + ADOHCY | ||
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| + | [[1svu]] - HhDNMT (mutant) | ||
===Methyladenine DNMT=== | ===Methyladenine DNMT=== | ||
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[[1nw6]] - RsN6-adenine DNMT + sinefungin | [[1nw6]] - RsN6-adenine DNMT + sinefungin | ||
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| + | [[1nw8]] - RsN6-adenine DNMT (mutant) | ||
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| + | [[2ibs]], [[2ibt]], [[2ih2]], [[2ih4]], [[2ih5]], [[2np6]], [[2np7]] - adenine DNMT Taqi + DNA + cofactor analog – ''Thermus aquaticus'' | ||
[[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | [[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 12:51, 24 November 2011
DNA methyltransferase (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor.
Contents |
3D Structures of DNA methyltransferase
Updated November 2011
Methylguanine DNMT
1sfe – O6-methylguanine DNMT C terminal – Escherichia coli
1qnt, 1eh6, 3llr - hO6-methylguanine DNMT – human
1t38 - hO6-methylguanine DNMT (mutant) + DNA
1t39, 1yfh - hO6-methylguanine DNMT + DNA
1eh7 - hO6-methylguanine DNMT methylated
1eh8 - hO6-methylguanine DNMT benzylated
1wrj - O6-methylguanine DNMT - Sulfolobus tokodaii
2g7h - O6-methylguanine DNMT – Methanocaldococcus jannaschii
2kif, 2kim - O6-methylguanine DNMT – Vibrio parahaemolyticus - NMR
Methylcytosine DNMT
2qrv - h-cytosine DNMT
3epz - h-cytosine DNMT replecation foci-targeting sequence
3flg - h-cytosine DNMT ADD domain
3a1a - h-cytosine DNMT PWWP domain
1g55 - h-cytosine DNMT2 (mutant)
3av4, 1khc - m-cytosine DNMT – mouse
2c7o, 2c7p, 2c7q, 2c7r, 3pta – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine
2uyc, 2uyh, 2uz4 - Hh-cytosine DNMT (mutant) + DNA + S-adenonosyl cysteine
3a1b - h-cytosine DNMT ADD domain + histone H3
3pt6, 3pt9 – m-cytosine DNMT + DNA
3av5 - m-cytosine DNMT + S-adenonosyl cysteine
3av6 - m-cytosine DNMT + SAM
3swr - h-cytosine DNMT + sinefungin
1boo - cytosine DNMT (mutant) – Proteus vulgaris
1fjx – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - Haemophilus haemolyticus
1hmy – HhHaeiii DNMT + S-adenonosyl methionine
1m0e - HhDNMT (mutant) + DNA + inhibitor
2i9k - HhDNMT (mutant) + DNA
2hr1 - HhDNMT + DNA + ADOHCY
2z6q, 2z6u, 2zcj - HhDNMT (mutant) + DNA + ADOHCY
1svu - HhDNMT (mutant)
Methyladenine DNMT
1nw5 – RsN6-adenine DNMT + SAM – Rhodobacter sphaeroides
1nw6 - RsN6-adenine DNMT + sinefungin
1nw8 - RsN6-adenine DNMT (mutant)
2ibs, 2ibt, 2ih2, 2ih4, 2ih5, 2np6, 2np7 - adenine DNMT Taqi + DNA + cofactor analog – Thermus aquaticus
1nw7 - RsN6-adenine DNMT + S-adenonosyl cysteine
