3r4b

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Revision as of 05:28, 30 November 2011

Template:STRUCTURE 3r4b

Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911

Template:ABSTRACT PUBMED 21896904

About this Structure

3r4b is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

• Dierynck I, Van Marck H, Van Ginderen M, Jonckers TH, Nalam MN, Schiffer CA, Raoof A, Kraus G, Picchio G. TMC310911, a Novel Human Immunodeficiency Virus Type-1 Protease Inhibitor shows in Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors. Antimicrob Agents Chemother. 2011 Sep 6. PMID:21896904 doi:10.1128/AAC.00748-11