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3sw2
From Proteopedia
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Revision as of 07:05, 7 December 2011
X-ray crystal structure of human FXA in complex with 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide
Template:ABSTRACT PUBMED 22041058
About this Structure
3sw2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Shi Y, O'Connor SP, Sitkoff D, Zhang J, Shi M, Bisaha SN, Wang Y, Li C, Ruan Z, Michael Lawrence R, Klei HE, Kish K, Liu EC, Seiler SM, Schweizer L, Steinbacher TE, Schumacher WA, Robl JA, Macor JE, Atwal KS, Stein PD. Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors. Bioorg Med Chem Lett. 2011 Jun 28. PMID:22041058 doi:10.1016/j.bmcl.2011.06.098
Categories: Coagulation factor Xa | Homo sapiens | Klei, H E. | Blood clotting | Blood coagulation factor | Cleavage on pair of basic residue | Egf-like domain | Epidermal growth factor-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Hydroxylation | Serine protease | Zymogen
