3mw1

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[[Image:3mw1.jpg|left|200px]]
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[[Image:3mw1.png|left|200px]]
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{{ABSTRACT_PUBMED_19678708}}
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{{ABSTRACT_PUBMED_21999461}}
==About this Structure==
==About this Structure==
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[[3mw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW1 OCA].
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[[3mw1]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW1 OCA].
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==See Also==
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*[[Mitogen-activated protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19678708</ref><references group="xtra"/>
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<ref group="xtra">PMID:021999461</ref><ref group="xtra">PMID:019678708</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Caturla, J F.]]
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[[Category: Caturla, F.]]
[[Category: Fisher, M.]]
[[Category: Fisher, M.]]
[[Category: Lamers, M.]]
[[Category: Lamers, M.]]
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[[Category: Roca, R.]]
[[Category: Roca, R.]]
[[Category: Segarra, V.]]
[[Category: Segarra, V.]]
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[[Category: Inhibitor complex]]
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[[Category: P38 map kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 07:05, 7 December 2011

Image:3mw1.png

Template:STRUCTURE 3mw1

Contents

p38 kinase Crystal structure in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 21999461

About this Structure

3mw1 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lumeras W, Vidal L, Vidal B, Balague C, Orellana A, Maldonado M, Dominguez M, Segarra V, Caturla F. 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase. J Med Chem. 2011 Nov 24;54(22):7899-910. Epub 2011 Oct 31. PMID:21999461 doi:10.1021/jm200975u
  • Lumeras W, Caturla F, Vidal L, Esteve C, Balague C, Orellana A, Dominguez M, Roca R, Huerta JM, Godessart N, Vidal B. Design, Synthesis, and Structure-Activity Relationships of Aminopyridine N-Oxides, a Novel Scaffold for the Potent and Selective Inhibition of p38 Mitogen Activated Protein Kinase. J Med Chem. 2009 Aug 14. PMID:19678708 doi:10.1021/jm9008604

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