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2xx3

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Revision as of 08:04, 7 December 2011

Image:2xx3.jpg

Template:STRUCTURE 2xx3

HUMAN THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE BUTENYL PHOSPHONATE MONOPHOSPHATE AND ADP

Template:ABSTRACT PUBMED 21128666

About this Structure

2xx3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Topalis D, Pradere U, Roy V, Caillat C, Azzouzi A, Broggi J, Snoeck R, Andrei G, Lin J, Eriksson S, Alexandre JA, El-Amri C, Deville-Bonne D, Meyer P, Balzarini J, Agrofoglio LA. Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. J Med Chem. 2011 Jan 13;54(1):222-32. Epub 2010 Dec 3. PMID:21128666 doi:10.1021/jm1011462

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OCA

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