3sdg

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'''Unreleased structure'''
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[[Image:3sdg.jpg|left|200px]]
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The entry 3sdg is ON HOLD until Paper Publication
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{{STRUCTURE_3sdg| PDB=3sdg | SCENE= }}
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Authors: Flipo, M., Desroses, M., Lecat-Guillet, N., Villemagne, B., Blondiaux, N., Leroux, F., Piveteau, C., Mathys, V., Flament, M.P., Siepmann, J., Villeret, V., Wohlkonig, A., Wintjens, R., Soror, S.H., Christophe, T., Jeon, H.K., Locht, C., Brodin, P., D prez, B, Baulard, A.R., Willand, N
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===Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.===
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Description: Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
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{{ABSTRACT_PUBMED_22098589}}
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==About this Structure==
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[[3sdg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SDG OCA].
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==Reference==
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<ref group="xtra">PMID:022098589</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Baulard, A R.]]
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[[Category: Blondiaux, N.]]
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[[Category: Brodin, P.]]
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[[Category: Christophe, T.]]
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[[Category: Desroses, M.]]
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[[Category: Flament, M P.]]
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[[Category: Flipo, M.]]
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[[Category: Jeon, H K.]]
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[[Category: Lecat-Guillet, N.]]
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[[Category: Leroux, F.]]
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[[Category: Locht, C.]]
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[[Category: Mathys, V.]]
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[[Category: Piveteau, C.]]
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[[Category: Siepmann, J.]]
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[[Category: Soror, S H.]]
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[[Category: Villemagne, B.]]
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[[Category: Villeret, V.]]
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[[Category: Willand, N]]
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[[Category: Wintjens, R.]]
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[[Category: Wohlkonig, A.]]
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[[Category: Prez, BD.]]
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[[Category: Dna]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein]]
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[[Category: Inhibitor]]
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[[Category: Tetr-family]]
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[[Category: Transcription repressor-inhibitor complex]]
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[[Category: Transcritptional regulatory repressor]]

Revision as of 08:04, 7 December 2011

Template:STRUCTURE 3sdg

Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.

Template:ABSTRACT PUBMED 22098589

About this Structure

3sdg is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Flipo M, Desroses M, Lecat-Guillet N, Villemagne B, Blondiaux N, Leroux F, Piveteau C, Mathys V, Flament MP, Siepmann J, Villeret V, Wohlkonig A, Wintjens R, Soror SH, Christophe T, Jeon HK, Locht C, Brodin P, Deprez BP, Baulard A, Willand N. Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors. J Med Chem. 2011 Nov 20. PMID:22098589 doi:10.1021/jm200825u

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