2bfw
From Proteopedia
(New page: 200px<br /> <applet load="2bfw" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bfw, resolution 1.80Å" /> '''STRUCTURE OF THE C ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2BFW is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]] with SO4 and ACT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.21 2.4.1.21]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BFW OCA]]. | + | 2BFW is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]] with SO4 and ACT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Starch_synthase Starch synthase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.21 2.4.1.21]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BFW OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: Pyrococcus abyssi]] | [[Category: Pyrococcus abyssi]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Starch synthase]] | ||
[[Category: Ferrer, J.C.]] | [[Category: Ferrer, J.C.]] | ||
[[Category: Fita, I.]] | [[Category: Fita, I.]] | ||
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[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:45:01 2007'' |
Revision as of 10:40, 30 October 2007
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STRUCTURE OF THE C DOMAIN OF GLYCOGEN SYNTHASE FROM PYROCOCCUS ABYSSI
Overview
Glycogen and starch synthases are retaining glycosyltransferases that, catalyze the transfer of glucosyl residues to the non-reducing end of a, growing alpha-1,4-glucan chain, a central process of the carbon/energy, metabolism present in almost all living organisms. The crystal structure, of the glycogen synthase from Pyrococcus abyssi, the smallest known member, of this family of enzymes, revealed that its subunits possess a fold, common to other glycosyltransferases, a pair of beta/alpha/beta Rossmann, fold-type domains with the catalytic site at their interface., Nevertheless, the archaeal enzyme presents an unprecedented homotrimeric, molecular arrangement both in solution, as determined by analytical, ultracentrifugation, and in the crystal. The C-domains are not involved in, ... [(full description)]
About this Structure
2BFW is a [Single protein] structure of sequence from [Pyrococcus abyssi] with SO4 and ACT as [ligands]. Active as [Starch synthase], with EC number [2.4.1.21]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of an archaeal glycogen synthase: insights into oligomerization and substrate binding of eukaryotic glycogen synthases., Horcajada C, Guinovart JJ, Fita I, Ferrer JC, J Biol Chem. 2006 Feb 3;281(5):2923-31. Epub 2005 Nov 29. PMID:16319074
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