3rcd

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Revision as of 10:46, 14 December 2011

Template:STRUCTURE 3rcd

HER2 Kinase Domain Complexed with TAK-285

Template:ABSTRACT PUBMED 22003817

About this Structure

3rcd is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ishikawa T, Seto M, Banno H, Kawakita Y, Oorui M, Taniguchi T, Ohta Y, Tamura T, Nakayama A, Miki H, Kamiguchi H, Tanaka T, Habuka N, Sogabe S, Yano J, Aertgeerts K, Kamiyama K. Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold. J Med Chem. 2011 Nov 4. PMID:22003817 doi:10.1021/jm2008634

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OCA

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