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[[Image:Second step.jpg|thumb|second step of the carnitine shuttle|600px|right]]
 

Revision as of 11:34, 23 December 2011

carnitine acetytransferase in complex with carnintine, one of its substrates
carnitine acetytransferase in complex with carnintine, one of its substrates

Carnitine acyltransferases are a large family of enzymes that play a main role in cellular energy metabolism, i.e. fatty acid oxidation. These enzymes catalyze the reversible exchange of acyl groups between Coenzyme A and carnitine. Carnitine acyltransferases include three different classes of enzymes which are known as carnitine acetyltransferases (CrATs), carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). The three classes of differ in their acyl group specificity as well as their localization.[1]

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