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2xx2

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{{STRUCTURE_2xx2| PDB=2xx2 | SCENE= }}
{{STRUCTURE_2xx2| PDB=2xx2 | SCENE= }}
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===MACROLACTONE INHIBITOR BOUND TO HSP90 N-TERM===
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===Macrolactone Inhibitor bound to HSP90 N-term===

Revision as of 05:47, 28 December 2011

Image:2xx2.png

Template:STRUCTURE 2xx2

Macrolactone Inhibitor bound to HSP90 N-term

Template:ABSTRACT PUBMED 21932796

About this Structure

2xx2 is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Day JE, Sharp SY, Rowlands MG, Aherne W, Hayes A, Raynaud FI, Lewis W, Roe SM, Prodromou C, Pearl LH, Workman P, Moody CJ. Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies. ACS Chem Biol. 2011 Oct 4. PMID:21932796 doi:10.1021/cb200196e

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OCA

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