This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4a55
From Proteopedia
m (Protected "4a55" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | [[Image:4a55.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4a55", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_4a55| PDB=4a55 | SCENE= }} | ||
| - | + | ===Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22120714}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22120714 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_22120714}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[4a55]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A55 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022120714</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Berndt, A.]] | ||
| + | [[Category: Hon, W C.]] | ||
| + | [[Category: Williams, R L.]] | ||
| + | [[Category: Cancer mutation]] | ||
| + | [[Category: Enzyme regulation]] | ||
| + | [[Category: Growth factor signalling]] | ||
| + | [[Category: Lipid kinase]] | ||
| + | [[Category: Membrane binding]] | ||
| + | [[Category: Non-atp competitive ligand binding site]] | ||
| + | [[Category: Oncogene]] | ||
| + | [[Category: Pi3-kinase inhibitor]] | ||
| + | [[Category: Structure-activity relationship]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Tumour]] | ||
Revision as of 07:23, 28 December 2011
Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108
Template:ABSTRACT PUBMED 22120714
About this Structure
4a55 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Hon WC, Berndt A, Williams RL. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.532. PMID:22120714 doi:10.1038/onc.2011.532
Categories: Homo sapiens | Mus musculus | Berndt, A. | Hon, W C. | Williams, R L. | Cancer mutation | Enzyme regulation | Growth factor signalling | Lipid kinase | Membrane binding | Non-atp competitive ligand binding site | Oncogene | Pi3-kinase inhibitor | Structure-activity relationship | Transferase | Tumour
