3qcl

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'''Unreleased structure'''
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[[Image:3qcl.jpg|left|200px]]
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The entry 3qcl is ON HOLD until Paper Publication
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{{STRUCTURE_3qcl| PDB=3qcl | SCENE= }}
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Authors: Sheriff, S.
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===Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid===
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Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid
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{{ABSTRACT_PUBMED_21882820}}
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==About this Structure==
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[[3qcl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QCL OCA].
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==Reference==
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<ref group="xtra">PMID:021882820</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Sheriff, S.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]
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[[Category: Tyrosine receptor phosphatase]]

Revision as of 07:24, 28 December 2011

Image:3qcl.jpg

Template:STRUCTURE 3qcl

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid

Template:ABSTRACT PUBMED 21882820

About this Structure

3qcl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sheriff S, Beno BR, Zhai W, Kostich WA, McDonnell PA, Kish K, Goldfarb V, Gao M, Kiefer SE, Yanchunas J, Huang Y, Shi S, Zhu S, Dzierba C, Bronson J, Macor JE, Appiah KK, Westphal RS, O'Connell J, Gerritz SW. Small molecule receptor protein tyrosine phosphatase gamma (RPTPgamma) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop. J Med Chem. 2011 Oct 13;54(19):6548-62. Epub 2011 Sep 20. PMID:21882820 doi:10.1021/jm2003766
[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]

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OCA

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