3vhu
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3vhu.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3vhu", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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+ | --> | ||
+ | {{STRUCTURE_3vhu| PDB=3vhu | SCENE= }} | ||
- | + | ===Mineralocorticoid receptor ligand-binding domain with spironolactone=== | |
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_22074142}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 22074142 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_22074142}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3vhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VHU OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:022074142</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Habuka, N.]] | ||
+ | [[Category: Sogabe, S.]] | ||
+ | [[Category: Activating mutation]] | ||
+ | [[Category: Antagonist]] | ||
+ | [[Category: Hypertension]] | ||
+ | [[Category: Nuclear receptor]] | ||
+ | [[Category: Spironolactone]] | ||
+ | [[Category: Transcription factor]] | ||
+ | [[Category: Transcription-inhibitor complex]] |
Revision as of 07:28, 28 December 2011
Mineralocorticoid receptor ligand-binding domain with spironolactone
Template:ABSTRACT PUBMED 22074142
About this Structure
3vhu is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hasui T, Matsunaga N, Ora T, Ohyabu N, Nishigaki N, Imura Y, Igata Y, Matsui H, Motoyaji T, Tanaka T, Habuka N, Sogabe S, Ono M, Siedem CS, Tang TP, Gauthier C, De Meese LA, Boyd SA, Fukumoto S. Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists. J Med Chem. 2011 Dec 22;54(24):8616-31. Epub 2011 Nov 29. PMID:22074142 doi:10.1021/jm2011645