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{{STRUCTURE_1frn| PDB=1frn | SCENE= }} | {{STRUCTURE_1frn| PDB=1frn | SCENE= }} | ||
| - | Plant-type ferredoxin: NADP+ reductase has two structural domains. The first domain is an antiparallel beta barrel at the amino terminus of the protein that contains the binding domain for the FAD cofactor<ref>doi:10.1016/j.abb.2008.02.014</ref>. The second domain is at the carboxyl terminus of the protein and contains an alpha helix-beta strand fold<ref>doi:10.1016/j.abb.2008.02.014</ref>. This terminal domain is where the NADP+ binds<ref>doi:10.1021/bi9004232</ref> The active site for the enzyme occurs at the interface between the two domains.[8] | + | Plant-type ferredoxin: NADP+ reductase has two structural domains. The first domain is an antiparallel beta barrel at the amino terminus of the protein that contains the binding domain for the FAD cofactor<ref>{{cite Journal|doi:10.1016/j.abb.2008.02.014}}</ref>. The second domain is at the carboxyl terminus of the protein and contains an alpha helix-beta strand fold<ref>doi:10.1016/j.abb.2008.02.014</ref>. This terminal domain is where the NADP+ binds<ref>doi:10.1021/bi9004232</ref> The active site for the enzyme occurs at the interface between the two domains.[8] |
== References == | == References == | ||
<references /> | <references /> | ||
Revision as of 16:57, 28 December 2011
Contents |
Description
Ferredoxin NADP+ Reductase
Activity
Structure
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| 1frn, resolution 2.00Å () | |||||||||
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| Ligands: | , , | ||||||||
| Activity: | Ferredoxin--NADP(+) reductase, with EC number 1.18.1.2 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Plant-type ferredoxin: NADP+ reductase has two structural domains. The first domain is an antiparallel beta barrel at the amino terminus of the protein that contains the binding domain for the FAD cofactor[1]. The second domain is at the carboxyl terminus of the protein and contains an alpha helix-beta strand fold[2]. This terminal domain is where the NADP+ binds[3] The active site for the enzyme occurs at the interface between the two domains.[8]
References
- ↑ Template:Cite Journal
- ↑ Aliverti A, Pandini V, Pennati A, de Rosa M, Zanetti G. Structural and functional diversity of ferredoxin-NADP(+) reductases. Arch Biochem Biophys. 2008 Jun 15;474(2):283-91. Epub 2008 Feb 16. PMID:18307973 doi:10.1016/j.abb.2008.02.014
- ↑ Paladini DH, Musumeci MA, Carrillo N, Ceccarelli EA. Induced fit and equilibrium dynamics for high catalytic efficiency in ferredoxin-NADP(H) reductases. Biochemistry. 2009 Jun 23;48(24):5760-8. PMID:19435322 doi:10.1021/bi9004232
