2occ
From Proteopedia
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| - | [[Image:2occ.gif|left|200px]]<br /><applet load="2occ" size=" | + | [[Image:2occ.gif|left|200px]]<br /><applet load="2occ" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2occ, resolution 2.3Å" /> | caption="2occ, resolution 2.3Å" /> | ||
'''BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE'''<br /> | '''BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2OCC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with CU, MG, NA, ZN, HEA and PER as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] Known structural/functional Site: <scene name='pdbsite=PXB:Peroxide Binding Site'>PXB</scene>. Full crystallographic information is available from [http:// | + | 2OCC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CU:'>CU</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HEA:'>HEA</scene> and <scene name='pdbligand=PER:'>PER</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] Known structural/functional Site: <scene name='pdbsite=PXB:Peroxide+Binding+Site'>PXB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OCC OCA]. |
==Reference== | ==Reference== | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:46:37 2008'' |
Revision as of 08:46, 3 February 2008
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BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE
Overview
Crystal structures of bovine heart cytochrome c oxidase in the fully, oxidized, fully reduced, azide-bound, and carbon monoxide-bound states, were determined at 2.30, 2.35, 2.9, and 2.8 angstrom resolution, respectively. An aspartate residue apart from the O2 reduction site, exchanges its effective accessibility to the matrix aqueous phase for one, to the cytosolic phase concomitantly with a significant decrease in the pK, of its carboxyl group, on reduction of the metal sites. The movement, indicates the aspartate as the proton pumping site. A tyrosine acidified, by a covalently linked imidazole nitrogen is a possible proton donor for, the O2 reduction by the enzyme.
About this Structure
2OCC is a Protein complex structure of sequences from Bos taurus with , , , , and as ligands. Active as Cytochrome-c oxidase, with EC number 1.9.3.1 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase., Yoshikawa S, Shinzawa-Itoh K, Nakashima R, Yaono R, Yamashita E, Inoue N, Yao M, Fei MJ, Libeu CP, Mizushima T, Yamaguchi H, Tomizaki T, Tsukihara T, Science. 1998 Jun 12;280(5370):1723-9. PMID:9624044
Page seeded by OCA on Sun Feb 3 10:46:37 2008
Categories: Bos taurus | Cytochrome-c oxidase | Protein complex | Tsukihara, T. | Yao, M. | CU | HEA | MG | NA | PER | ZN | Cytochrome c oxidase | Cytochrome(c)-oxygen | Oxidoreductase
