4a4l
From Proteopedia
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| - | + | [[Image:4a4l.png|left|200px]] | |
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| + | The line below this paragraph, containing "STRUCTURE_4a4l", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_4a4l| PDB=4a4l | SCENE= }} | ||
| - | + | ===CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22154349}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22154349 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22154349}} | ||
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| + | ==About this Structure== | ||
| + | [[4a4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4L OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022154349</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Polo kinase]] | ||
| + | [[Category: Bertrand, J A.]] | ||
| + | [[Category: Bossi, R T.]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:16, 11 January 2012
CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR
Template:ABSTRACT PUBMED 22154349
About this Structure
4a4l is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Caruso M, Valsasina B, Ballinari D, Bertrand J, Brasca MG, Caldarelli M, Cappella P, Fiorentini F, Gianellini LM, Scolaro A, Beria I. 5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):96-101. Epub 2011 Nov 23. PMID:22154349 doi:10.1016/j.bmcl.2011.11.065
