Epidermal growth factor

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(New page: {{STRUCTURE_2kv4| PDB=2kv4 | SIZE=400| SCENE= |right|CAPTION=Human epidermal growth factor, 2kv4 }} '''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds t...)
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{{STRUCTURE_2jl9| PDB=1jl9 | SIZE=400| SCENE= |right|CAPTION=Human epidermal growth factor, [[1jl9]] }}
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{{STRUCTURE_2kv4| PDB=2kv4 | SIZE=400| SCENE= |right|CAPTION=Human epidermal growth factor, [[2kv4]] }}
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Revision as of 15:17, 11 January 2012

Template:STRUCTURE 2jl9


Epidermal growth factor (EGF) plays a role in cell growth. It binds to its receptor (EGFR). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds.

Contents

3D structures of epidermal growth factor

1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR
1a3p – mEGF (mutant) – NMR
1jl9, 2kv4 – hEGF
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR

Heparin-binding EGF-like growth factor

1xdt –h HB-EGF extracellular domain + diphtheria toxin

EGF-like Cripto protein

2j5h – mCR-EGF residues 96-134 - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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