Epidermal growth factor

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Line 13: Line 13:
1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR<br />
1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR<br />
1a3p – mEGF (mutant) – NMR<br />
1a3p – mEGF (mutant) – NMR<br />
-
1jl9, 2kv4 – hEGF<br/ >
+
1jl9 – hEGF<br/ >
 +
2kv4 – hEGF - NMR<br/ >
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR

Revision as of 15:18, 11 January 2012

Template:STRUCTURE 2jl9


Epidermal growth factor (EGF) plays a role in cell growth. It binds to its receptor (EGFR). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds.

Contents

3D structures of epidermal growth factor

1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR
1a3p – mEGF (mutant) – NMR
1jl9 – hEGF
2kv4 – hEGF - NMR
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR

Heparin-binding EGF-like growth factor

1xdt –h HB-EGF extracellular domain + diphtheria toxin

EGF-like Cripto protein

2j5h – mCR-EGF residues 96-134 - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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