Epidermal growth factor
From Proteopedia
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'''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor (EGFR). | '''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor (EGFR). | ||
EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. | EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. | ||
| - | All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. | + | All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in [[EGF1]]. |
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
Revision as of 15:30, 11 January 2012
Epidermal growth factor (EGF) plays a role in cell growth. It binds to its receptor (EGFR).
EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity.
All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in EGF1.
Contents |
3D structures of epidermal growth factor
1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR
1a3p – mEGF (mutant) – NMR
1jl9 – hEGF
2kv4 – hEGF - NMR
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR
Heparin-binding EGF-like growth factor
1xdt – hHB-EGF extracellular domain + diphtheria toxin
EGF-like Cripto protein
2j5h – mCR-EGF residues 96-134 - NMR
