MDM4
From Proteopedia
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Michal Harel (Talk | contribs)
(New page: {{STRUCTURE_3dab| PDB=3dab | SIZE=400| SCENE=1 |right|CAPTION=Human MDM4 complex with p53 transactivation domain , 3dab }} '''MDM4''' is a 490 amino acid protein containing a RING f...)
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Revision as of 21:15, 13 January 2012
MDM4 is a 490 amino acid protein containing a RING finger domain and a nuclear localization signal. MDM4 interacts with protein MDM2. Both of these proteins show structure similarity and contain a p53-binding domain in their N terminal.
Contents |
3D Structures of MDM4
2cr8 – hMDM4 ZF-RNBP domain – NMR 3dab – hMDM4 + p53 transactivation domain 3fdo, 3jzo, 3jzp, 3jzq, 3jzr, 3jzs – hMDM4 p53-binding domain + peptide 3lbj - hMDM4 p53-binding domain + inhibitor 3dac – hMDM4 (mutant) + p53 transactivation domain 2vyr – hMDM4 N terminal + antibody 3fe7, 3fea, 3eqy - hMDM4 N terminal (mutant) + peptide 2vje, 2vjf – hMDM2 residues 383-446 + hMDM4 residues 428-490
