3ufl

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'''Unreleased structure'''
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[[Image:3ufl.jpg|left|200px]]
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The entry 3ufl is ON HOLD until Paper Publication
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{{STRUCTURE_3ufl| PDB=3ufl | SCENE= }}
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Authors: Allison, T., Munshi, S., Soisson, S.M.
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===Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency===
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Description: Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency
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{{ABSTRACT_PUBMED_22130130}}
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==About this Structure==
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[[3ufl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UFL OCA].
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==Reference==
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<ref group="xtra">PMID:022130130</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Allison, T.]]
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[[Category: Munshi, S.]]
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[[Category: Soisson, S M.]]
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[[Category: Aspartyl protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 10:45, 18 January 2012

Image:3ufl.jpg

Template:STRUCTURE 3ufl

Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency

Template:ABSTRACT PUBMED 22130130

About this Structure

3ufl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Stachel SJ, Steele TG, Petrocchi A, Haugabook SJ, McGaughey G, Katharine Holloway M, Allison T, Munshi S, Zuck P, Colussi D, Tugasheva K, Wolfe A, Graham SL, Vacca JP. Discovery of pyrrolidine-based beta-secretase inhibitors: Lead advancement through conformational design for maintenance of ligand binding efficiency. Bioorg Med Chem Lett. 2012 Jan 1;22(1):240-4. Epub 2011 Nov 12. PMID:22130130 doi:10.1016/j.bmcl.2011.11.024

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OCA

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